ABSTRACT
Objective To explore the association between gestational weight gain (GWG) and adverse pregnancy outcomes.Methods A prospective study was conducted among 1 220 healthy singleton pregnant women in the first trimester of pregnancy,from Chengdu city,Sichuan province.Pre-gestational body mass and other basic information were collected through a set of questionnaires.Weight at the last week before delivery was measured and GWG was classified by IOM criteria (2009).Related information on pregnancy outcomes was collected after delivery,through the hospital information system.Multiple non-conditional logistic regression models were used to test the association between GWG and adverse pregnancy outcomes.Results In total,data on 1 045 pregnant women were analyzed.Compared with adequate GWG,excessive GWG was associated with the increased risks of cord entanglement and large for gestational age (OR=1.641,95％CI:1.197-2.252;OR=1.678,95％ CI:0.132-2.488),respectively.Additionally,when compared with the adequate GWG,insufficient GWG was associated with the increased risk of preterm delivery (OR=3.189,95％CI:1.604-6.341).Conclusions Both excessive and insufficient GWG appeared associated with the pregnancy outcomes.Weight monitoring should be strengthened for pregnant women to reduce related risks on adverse pregnancy outcomes.
ABSTRACT
Objective To explore the association between gestational weight gain (GWG) and adverse pregnancy outcomes.Methods A prospective study was conducted among 1 220 healthy singleton pregnant women in the first trimester of pregnancy,from Chengdu city,Sichuan province.Pre-gestational body mass and other basic information were collected through a set of questionnaires.Weight at the last week before delivery was measured and GWG was classified by IOM criteria (2009).Related information on pregnancy outcomes was collected after delivery,through the hospital information system.Multiple non-conditional logistic regression models were used to test the association between GWG and adverse pregnancy outcomes.Results In total,data on 1 045 pregnant women were analyzed.Compared with adequate GWG,excessive GWG was associated with the increased risks of cord entanglement and large for gestational age (OR=1.641,95％CI:1.197-2.252;OR=1.678,95％ CI:0.132-2.488),respectively.Additionally,when compared with the adequate GWG,insufficient GWG was associated with the increased risk of preterm delivery (OR=3.189,95％CI:1.604-6.341).Conclusions Both excessive and insufficient GWG appeared associated with the pregnancy outcomes.Weight monitoring should be strengthened for pregnant women to reduce related risks on adverse pregnancy outcomes.
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on the onset time of lactation (OL).</p><p><b>METHODS</b>In this longitudinal study, 751 healthy single pregnant women were selected from three hospitals in Chengdu as subjects of baseline survey during March and September 2013 and were followed before and after delivery, respectively. Finally, data from a total of 473 pregnant women were analyzed. Data on pre-pregnancy weight, delivery mode, birth weight of neonate, information of lactation and maternal demographic characteristics were collected through questionnaire and medical records. Height and weight at the last week before delivery were measured and GWG were calculated. After controlling the potential confounders, a serial of multi-factor ordinal logistic regression models were performed to test the associations between pre-pregnancy BMI, GWG and OL.</p><p><b>RESULTS</b>The proportions of OL at the < 1, 1-, 24-, 48- and ≥ 72 h groups were 16.3%, 37.0%, 17.5%, 18.6% and 10.6%, respectively. When compared to women with normal weight, the ORs for prolonged OL were 2.85 (1.91-4.27) and 3.42 (1.69-6.90) among pre-pregnant underweight and overweight/obese women, respectively. When compared to women with normal weight and adequate GWG, pre-pregnant underweight women with adequate and excessive GWG showed greater odds of prolonged OL (OR = 2.34, 95% CI: 1.31-4.18; OR = 3.42, 95% CI: 1.67-7.00), respectively. Pre-pregnant overweight/obese women with excessive GWG had increased the odds of prolonged OL (OR = 3.10, 95% CI: 1.15-8.37).</p><p><b>CONCLUSION</b>Pre-pregnant BMI appeared an independently factor, associated with OL while GWG might have an effect on OL, when pre-pregnant BMI was considered.</p>